- Opportunity to work in a highly dynamic work environment
- Job security - 3 year contract with strong prospect of renewal
- Attractive salary packaging & superannuation options
About QIMR Berghofer:
QIMR Berghofer is a world-leading translational medical research institute focused on improving health by developing new diagnostics, better treatments and prevention strategies, specifically in the areas of cancer, infectious diseases, mental health and chronic disorders. Based in Herston, Brisbane and working in close collaboration with clinicians and other research institutes, QIMR Berghofer is home to more than 600 scientists, students and support staff.
About the Cancer Immunorogulation and Immunotherapy Laboratory:
The laboratory headed by A/Prof Michele Teng investigates how tumour-induced immune suppression impedes the effective treatment of established cancer. We aim to increase the proportion of cancer patients who will respond to immunotherapy by exploring novel pathways & combinations that can be rationally targeted. Subsequently, their scheduling & safety can be evaluated using unique mouse models the laboratory has developed. Ultimately, our goal is to translate our pre-clinical findings & test in clinical trials through our clinical colleagues. Our institute is part of a major hospital campus.
Role Purpose / Responsibilities:
Applications are invited for a motivated research officer to investigate how targeting novel immunoregulatory pathways mediated by T and myeloid cells attenuate the balance of tumor immunity and autoimmunity.
This position will involve large number of in vitro, in vivo and ex vivo experiments, involving animal handling, animal experimentation (i.v, s.c, i.p injections), mammary fatpad surgery, immune subset isolation, tumour infiltrating leukocyte (TIL) isolation, serum and tissue analysis, and complex flow cytometry.
Responsibilities include but are not limited to:
- ability to manage multiple research projects arising from collaborations with academia or with pharmaceutical industry
- supervision of students
- application for relevant grant funding
Our institute has first rate facilities and infrastructure, including the largest gene targeted mouse colony collection in Australia and worldwide.
The applicant will have the opportunity to interact with scientists and medical oncologists as part of the larger Cancer Immunology Group comprising of 3 laboratories (35 staff and students total). In addition, through our local, national and international clinical collaborations, the applicant will have the ability to translate any novel immuno-oncology targets discovered through our in-house multiplex immunohistochemistry capabilities and access to various fresh and FFPE human cancers. The laboratory also has commercial funding and the applicant will have the opportunity to undertake industry-sponsored projects.
We are seeking an applicant who is independent, thinks creatively and up to the challenge of making new scientific discoveries.
To be successful in this role you are expected to have;
- Ph.D (0-3 years of experience) from an accredited university in immunology, immuno-oncology or related discipline.
- Hands on experience working with various murine tumor models, including administering immunotherapeutic agents (i.v., i.p., s.c. and oral gavage), eye or cheek bleeding
- Expertise in performing complex flow cytometry analysis on various immune organs and tumour infiltrating leukocytes
Desirable skills and knowledge include;
- Computational skills for analyzing bulk and single-cell RNA sequencing datausing various data software packages
- Experience in human immunology and various immune in vitro assays
You will have a strong publication track record (relative to opportunity). You need to have demonstrable experience in the analysis of experimental results and preparation of research presentations. You should demonstrate excellent written and oral communication skills and have the ability to work independently as well as within established collaborative academic teams.
Remuneration: Salary range is $82,506 to $88,522 per annum. This is a full-time appointment for three years with strong prospect of renewal for another two.
For further information: Contact A/Prof. Michele Teng at email@example.com
Closing Date: 15 November 2020
To submit an application: use the APPLY button. All applicants must supply the following documents: Cover Letter, Resume and Selection Criteria.
What we offer:
- Salary Packaging
- Bonus Superannuation
- State of the art facilities
- Stimulating work setting focussed on cutting edge medical research
- Supportive/collaborative team environment